4DB Center: Physics of Metastasis over Time and Space

Dr. Shork is Professor, Molecular and Experimental Medicine at TSRI and Director of Bioinformatics and Biostatistics for the Scripps Translational Science Institute, an NIH Clinical Translational Science Award Center devoted to translational research. Over 250 publications have come out of Dr. Schork’s laboratory focusing on the development and implementation of data analysis methods that can be used for understanding the genetic determinants of complex human traits and diseases such as cancer, neuropsychiatric disease, and cardiovascular disease. Methodologies that Dr. Schork has developed, or is working currently, focus on both the design of studies making use of contemporary high-throughput, high-dimensional genomic technologies such as DNA sequencing technologies, multilocus genotyping technologies, and DNA microarrays, as well the interpretation of the results obtained from studies making use of these technologies. Recently, Dr. Schork and his laboratory have focused on the characterization of the effect of DNA sequence alterations contributing to tumorigenesis using computational and modeling strategies in addition to developing methods to accommodate a large number of variables collected on relatively few individuals. Dr. Schork has a long history of collaborative research in which he has contributed data analysis methodology and data analysis expertise. Dr. Schork has trained 19 graduate students and 11 post doctoral students.