4DB Center: Physics of Metastasis over Time and Space

Dr. Griffin has been advising the PI and senior co-investigator on the study of the third microenvironment and the design of experiments as they relate to the overarching framework of the 4DB. Dr. Griffin received a B.S. in Physics from Santa Clara University and then a Ph.D. in Biophysics from the University of California, Davis, in 1969. Following four years of post-doctoral training in spectroscopic studies of protein structure and function with Dr. Elkan R. Blout at Harvard Medical School and with Dr. Christian B. Anfinsen at the NIH in Bethesda, he continued NMR studies of peptide and protein structure at the French Atomic Energy Commission Laboratory (C.E.A.) in Saclay, France. In 1974, he was appointed Assistant Professor in the Department of Experimental Pathology at The Scripps Research Institute where he currently is Professor of Molecular and Experimental Medicine. He also is an Adjunct Professor of Medicine at the University of California at San Diego.

Over the past 30 years at Scripps, Dr. Griffin’s research interests with an emphasis on blood components and blood proteins have evolved in the hematology arena and have included a wide range of problems. Translational research in his lab spans from bench to bedside and includes basic structure-function studies of proteins, lipids and lipoproteins, blood cells, animal injury model studies, and clinical investigations of blood-borne biomarkers and genetic risk factors for thrombosis. Based on his clinical research efforts, he was among the first Ph.D. researchers to be awarded honorary membership in the American Society of Clinical Investigation. He currently chairs the Hemostasis and Thrombosis Study Section that is part of the Hematology IRG of CSR at NIH.